New evidence from two clinical trials in Europe suggests cannabis could be a valuable alternative for treating chronic low back pain. The research, featured in Nature Medicine, found a proprietary cannabis oil to outperform both placebos and opioids over a six-month period, with fewer gastrointestinal side effects. Patients using cannabis saw an average 30% reduction in pain, compared to about 20% for those on placebo. Unlike opioids, cannabis did not show risks for dependency or withdrawal, and most participants did not experience being “stoned.” Experts note the cannabis formula’s effect is promising but not a panacea—about seven people need the drug for one to achieve meaningful relief.

With the FDA requiring more trials before approval in the U.S., pain specialists and patient advocates urge further rigorous research. Read the full report on NPR here.